Michael, this wasn't my field and I think there are others in this forum who are closer to the technology. But, I was also interested and did some searching. Apparently its a three-electrode system, so I assume that the filament is a three part electrode with a chemical (glucose oxidase) pasted on one. Glucose reacts with the chemical and generates a small electrical current to another electrode. A third is used as a reference. The current is proportional to the glucose concentration. Through a reasonable magnifying glass, you can see that one face of the (flat ?) filament is a bit shiny and the other side has two dark coatings separated by a gap. I assume those are the three electrodes and the shiny one is the reference, but I might be completely wrong since my magnifying glass/eyesight are modest. Maybe the gap that I saw was just damage.
There's an interesting animation of the chemical reaction here: (doesn't seem to find the right video on my phone).
https://www.hybridmedicalanimation.com/work/animation/wired-enzyme-technology/
..and an old reference paper here which seems to relate to L1:
https://journals.sagepub.com/doi/pdf/10.1177/193229681300700511
And another re libra (still more than 10 years old research):
https://www.liebertpub.com/doi/full/10.1089/dia.2017.0025
Original Message:
Sent: 17-05-2023 19:42
From: Michael
Subject: CGM sensor covers
Hi Jock,
A bit off the topic but you may be just the person to ask with your background. How does the very fine filament on the sensor that is injected tests the fluids? I find it puzzling how the filament works. Does the filament suck up the fluid in the body as it flows past to test the sugars?
Further, I would improve the design of the sensor by making it silent when pressing the plunger to inject the filament. I find the sound of the spring thudding against my arm very unnerving. Maybe, the designer of the Libre2 model never actually had to to use the sensor.
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Michael
Original Message:
Sent: 17-05-2023 11:30
From: Jock
Subject: CGM sensor covers
Cris, I had two sensors recently that "ended" after about a week. Abbott replaces them within a couple of days. For the last replacement, I asked why they failed, so I had to return the failed sensor and labelled the box as instructed to be given feed-back on the cause. In practise, I would be very surprised to receive a reply and wonder if they would really have the time to investigate.
I also ask about the L3, but get the answer is always "we have no information about that".
I'm probably more tolerant than average about failues becasue I used to develop on-line industrial annalitycal instruments and I know the challenges involved in making the callibration match the results to a different analytical technique (the lab). The plots we see on the app will be highly smoothed and there are calibration plots on the info sheet that's in the box that show the scatter between a laboratory technique and the L2 sensor - looks normal to me.
The CGMs are really a process control tool and I think its remarkable that we can use it for insulin dosing. There are so many variables that effect our control. (I'm no doing desk work and my BGL has started to rise...).
CGMs have been a game-changer and I'm very grateful for the technology and the efforts by DA to have them subsidised.
BUT, I digress - Barbara I hope you solve your adhesion problem and that you'll let us know when you do - keep trying.
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Jock
Original Message:
Sent: 17-05-2023 07:07
From: Crispin
Subject: CGM sensor covers
Thanks Jock
Pretty much what I do. I get my wife to put tape on as well...bit of a pain to get off sometimes.
Have you had any duds? I have very few now but the % was much higher before and at the beginning of the subsidy.
Abbot never fail to replace them even if the problem is near the end of the life of the sensor.
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Cheers
Cris
Original Message:
Sent: 16-05-2023 13:27
From: Jock
Subject: CGM sensor covers
Cris, you reminded me of another hint from the Abbott trainers to get a better view of the site behind the arm:
Before application, bend the elbow at about 90 deg and then rotate the shoulder to raise arm forward so that the upper arm is horizontal (humerus horizontal and pointing forward, ulna and radius vertical). Then its easy for the other hand to push the applicator upwards under the triceps. The sensor will be facing backwards when the arm is at rest beside the body.
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Jock
Original Message:
Sent: 16-05-2023 11:53
From: Crispin
Subject: CGM sensor covers
Hi Barbara
The only thing I can add to the info re attaching, is that there will be some dud sensors and some errors placing the sensors. In those events Abbot will replace the duds and probably the ones that are due to placement errors. They replaced one of mine that I suspect may have not been attached properly. Pretty hard to get every one right when you are aiming for places like the rear of the upper underarm and can't see there properly.
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Cheers
Cris
Original Message:
Sent: 15-05-2023 12:20
From: Barbara
Subject: CGM sensor covers
Good afternoon
This is my second post but I always read the posts from others and find them very helpful. I have only been a Type 1 for 5 years (I am 75) so it is all new. I have a CGM sensor and love it (Libre 2) But am finding it difficult keeping them attached. I know sensor covers are available but which ones are the best?
Thank you in advance for your advice.
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Barbara
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